Basic Information
VIS ID
TVIS44031107
Fusion event
HTLV-1-THSD7A integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr7
Cytoband
p21.3
Reference genome
NCBI36/hg18
Start
11663593/11657441 (Hg38)
End
11663593/11657441 (Hg38)
Orient
+
Location type
Intronic
Target gene
THSD7A
miRNAs that regulate target gene
hsa-mir-574-5p ; hsa-mir-448 ; hsa-mir-6867-5p ; hsa-mir-190a-3p ; hsa-mir-223-5p ; hsa-mir-5011-5p ; hsa-mir-586 ; hsa-mir-1277-5p ; hsa-mir-7152-5p ; hsa-mir-3074-5p ; hsa-mir-3119 ; hsa-mir-3158-3p ; hsa-mir-532-5p ; hsa-mir-5195-3p ; hsa-mir-145-5p ; hsa-mir-584-3p ; hsa-mir-641 ; hsa-mir-3617-5p ; hsa-mir-3692-3p ; hsa-mir-5581-5p ; hsa-mir-4297 ; hsa-mir-153-5p ; hsa-mir-210-3p
Nearest miRNA
hsa-mir-339/Upstream/4590396; hsa-mir-10399/Downstream/6469779;
Nearest TSS
ENST00000635602/Upstream/114382; ENST00000442107/Downstream/93912;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/683180, chr7-CpG: 25/Downstream/174340
Upstream sequence
TCCAGGAATAGGGAAGGATATAAACAAAAACAGCAAGTACGGGCTGTGTAAATAGGCAGTGGAGCATAGACATGGGAAAGAAACAGGGACCCTGGAATCA
Downstream sequence
GGTTGTAGAAGGTGTGGAACCATTACTATGGGTAAATCCTTGACTAATATACTCTTCAATGCCTAACTATAGGTATATCCTGCTCTCCTTCAATAACCTG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate