Basic Information
VIS ID
TVIS44031108
Fusion event
HTLV-1-MIOS integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr7
Cytoband
p21.3
Reference genome
NCBI36/hg18
Start
7578107/7571951 (Hg38)
End
7578107/7571951 (Hg38)
Orient
+
Location type
Intronic
Target gene
MIOS
miRNAs that regulate target gene
hsa-mir-98-5p ; hsa-let-7b-5p
Nearest miRNA
hsa-mir-339/Upstream/504906; hsa-mir-10399/Downstream/10555269;
Nearest TSS
ENST00000635602/Upstream/4468; ENST00000461907/Downstream/9778;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/4559, chr7-CpG: 69/Downstream/68258
Upstream sequence
AATCTCCATTGTTCATTACGATGAccacatatggttatttatattaaaatttgttaaaattaaggtttaaaatttgaattagtcacatttctagtgctca
Downstream sequence
gtagctacatgtggctagtggctaccatattggacagcatgaacatgaaacatttctgtcattgcagaaagttttattgggcagtgctgCTTTAAACTAT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate