Basic Information
VIS ID
TVIS44031132
Fusion event
HTLV-1-PSD3 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr8
Cytoband
p22
Reference genome
NCBI36/hg18
Start
18982998/19081208 (Hg38)
End
18982998/19081208 (Hg38)
Orient
-
Location type
Intronic
Target gene
PSD3
miRNAs that regulate target gene
hsa-mir-130b-5p ; hsa-mir-20b-5p ; hsa-mir-326 ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-let-7e-5p ; hsa-let-7b-5p ; hsa-mir-95-5p ; hsa-mir-218-5p ; hsa-mir-152-5p ; hsa-mir-597-3p ; hsa-mir-182-3p ; hsa-mir-765 ; hsa-mir-4784 ; hsa-mir-3150b-3p ; hsa-mir-4680-3p ; hsa-mir-5187-3p ; hsa-mir-4427 ; hsa-mir-4518 ; hsa-mir-1266-5p ; hsa-mir-3664-3p ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-216a-5p ; hsa-mir-744-3p ; hsa-mir-4423-5p ; hsa-mir-6501-5p ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p ; hsa-mir-548t-3p ; hsa-mir-548ap-3p ; hsa-mir-548aa ; hsa-mir-4759 ; hsa-mir-655-3p ; hsa-mir-374c-5p ; hsa-mir-429 ; hsa-mir-200c-3p ; hsa-mir-8084 ; hsa-mir-200b-3p ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-520e ; hsa-mir-302a-3p ; hsa-mir-520a-3p ; hsa-mir-372-3p ; hsa-mir-520b ; hsa-mir-520c-3p ; hsa-mir-520d-3p ; hsa-mir-373-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302b-3p ; hsa-mir-302c-3p
Nearest miRNA
hsa-mir-124-1/Upstream/1399551; hsa-mir-10400/Downstream/3163758;
Nearest TSS
ENST00000518652/Upstream/66748; ENST00000518324/Downstream/3522;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/66672, chr8-CpG: 42/Downstream/156238
Upstream sequence
GGCTCTGGTCCCGGCCCATAGAATATTCTCTGATTCACACTGACAGACTCACCACAGAAATGTTAGAGCCGTCCGTTGGCACCACCCTGAGCTGAGACTC
Downstream sequence
CACGTCCCCAACACCTAGGCCTTCACTGCTTCTAGAAAGCTGGCTGGACTCATTCGTACAAGGTTAGGTCACTAGACCTAAAGTCTTGAGTGTCTTTCTC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate