Basic Information
VIS ID
TVIS44031138
Fusion event
HTLV-1-DENND3 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr8
Cytoband
q24.3
Reference genome
NCBI36/hg18
Start
142243613/141164332 (Hg38)
End
142243613/141164332 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA8D
Target gene
DENND3
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-1204/Upstream/431679; hsa-mir-10400/Downstream/621910;
Nearest TSS
ENST00000518652/Upstream/6937; ENST00000523066/Downstream/9173;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/35089, chr8-CpG: 24/Downstream/9001
Upstream sequence
ggaatgtcccgtggttgggacagagtgcgctttgttcttctgtccacctgctactgagcattggggttgtttccatttgtgactattacaaaaaaaTAAT
Downstream sequence
CACCTTGGgggctttgccctggcaggcgattgaagctgcctgaagagccccttgatcctttgggggtttgtttttacagctttggggtgggccgagaaca
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate