Basic Information
VIS ID
TVIS44031140
Fusion event
HTLV-1-MTBP integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr8
Cytoband
q24.12
Reference genome
NCBI36/hg18
Start
121544718/120463297 (Hg38)
End
121544718/120463297 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA8C ; FRA8E
Target gene
MTBP
Nearest miRNA
hsa-mir-12123/Upstream/1138032; hsa-mir-10400/Downstream/2752491;
Nearest TSS
ENST00000518652/Upstream/4021; ENST00000519188/Downstream/24864;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/17880, chr8-CpG: 121/Downstream/347878
Upstream sequence
TGAAGAAACCTAAGAATCAGTCAGCTGATGTATCATTTTATGTATTTAAGTAAATATAAATGGTATCACATGTATCTGCAAATATATTCAACATATTTTA
Downstream sequence
AACTCTCTTTTAAAAATATATAAGCATGTTTAGAAATACACCTAAGAACAGAACATTTTATATAAAAAGAAATTGTTATTGGCTGGAAATGAAACACTAG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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