Basic Information
VIS ID
TVIS44031149
Fusion event
HTLV-1-ABCA1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr9
Cytoband
q31.1
Reference genome
NCBI36/hg18
Start
106696220/104894118 (Hg38)
End
106696220/104894118 (Hg38)
Orient
-
Location type
Intronic
Target gene
ABCA1
miRNAs that regulate target gene
hsa-mir-33b-5p ; hsa-mir-33a-5p ; hsa-mir-26a-5p ; hsa-mir-26b-5p ; hsa-mir-19a-3p ; hsa-mir-27a-3p ; hsa-mir-128-3p ; hsa-mir-27b-3p ; hsa-mir-613 ; hsa-mir-20a-5p ; hsa-mir-106b-5p ; hsa-mir-519d-3p ; hsa-mir-93-5p ; hsa-mir-17-5p ; hsa-mir-20b-5p ; hsa-mir-33a-3p ; hsa-mir-33b-3p ; hsa-mir-148a-5p ; hsa-mir-302a-3p
Nearest miRNA
hsa-let-7a-1/Upstream/6664901; hsa-mir-12126/Downstream/1706810;
Nearest TSS
ENST00000422679/Upstream/63129; ENST00000435915/Downstream/33435;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/129620, chr9-CpG: 23/Downstream/32370
Upstream sequence
gaagtgaagaaactgaggtttgaacaagttacgagccataagaaactgcaccaatgtttgaacccagatctactgacacttaagtgtgtgcttttgtacc
Downstream sequence
catcatgctgccATCACAAAGCTATGTTTAGGACATATACCTTTTAAGATATGCCACTTAAAAGAAACCTAGCACTTGCCAGCCCTGCTGAGCACTGATC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate