Basic Information
VIS ID
TVIS44031162
Fusion event
HTLV-1-SLC35G1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr10
Cytoband
q23.33
Reference genome
NCBI36/hg18
Start
95651485/93901738 (Hg38)
End
95651485/93901738 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA10D
Target gene
SLC35G1
miRNAs that regulate target gene
hsa-mir-193b-3p ; hsa-mir-340-5p ; hsa-mir-124-3p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-664a-3p ; hsa-mir-500b-5p ; hsa-mir-4760-3p ; hsa-mir-362-5p ; hsa-mir-4753-5p ; hsa-mir-500a-5p ; hsa-mir-6715b-3p ; hsa-mir-302a-5p ; hsa-mir-7844-5p ; hsa-mir-6509-5p ; hsa-mir-670-5p ; hsa-mir-331-5p ; hsa-mir-642b-5p ; hsa-mir-23b-5p ; hsa-mir-23a-5p ; hsa-mir-6077 ; hsa-mir-7-5p ; hsa-mir-4424 ; hsa-mir-4693-3p ; hsa-mir-6761-5p ; hsa-mir-4324 ; hsa-mir-4732-3p ; hsa-mir-345-3p ; hsa-mir-196b-5p ; hsa-mir-196a-5p ; hsa-mir-6831-5p ; hsa-mir-3927-3p ; hsa-mir-6854-5p ; hsa-mir-125a-5p ; hsa-mir-125b-5p ; hsa-mir-4319 ; hsa-mir-4777-5p ; hsa-mir-526a ; hsa-mir-523-5p ; hsa-mir-522-5p ; hsa-mir-520c-5p ; hsa-mir-519c-5p ; hsa-mir-519b-5p ; hsa-mir-519a-5p ; hsa-mir-518f-5p ; hsa-mir-518e-5p ; hsa-mir-518d-5p ; hsa-mir-6831-3p ; hsa-mir-627-3p ; hsa-mir-150-5p ; hsa-mir-6814-5p ; hsa-mir-208b-5p ; hsa-mir-208a-5p ; hsa-mir-3150b-5p ; hsa-mir-3150a-5p
Nearest miRNA
hsa-mir-107/Upstream/4308911; hsa-mir-1287/Downstream/2162577;
Nearest TSS
ENST00000439456/Upstream/7716; ENST00000371375/Downstream/129074;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/7314, chr10-CpG: 88/Downstream/91852
Upstream sequence
TTAGTTAAGAATAGCTAGTCTGTTTGGTGTAACAATTTTTTGGTAGCTTTGGTTTTGGTTTTGGTTTTTTTTGTTGTTGTTGTTGGGGTCAAGTTGGTGA
Downstream sequence
GAGGAGAGCTCATTGTTTGAAGAAAAACCAAAACATTTTATGGCTAGTAATATTTATGTAATTTTTAAAATGTATTTTTGGTACTGATGGGATATGGGTG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate