Basic Information
VIS ID
TVIS44031168
Fusion event
HTLV-1-ABLIM1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr10
Cytoband
q25.3
Reference genome
NCBI36/hg18
Start
116266922/114517173 (Hg38)
End
116266922/114517173 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA10D ; FRA10A ; FRA10B
Target gene
ABLIM1
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-122-5p ; hsa-mir-615-3p ; hsa-mir-331-3p ; hsa-mir-320a ; hsa-mir-100-5p ; hsa-mir-34a-5p ; hsa-mir-5581-3p ; hsa-mir-222-3p ; hsa-mir-221-3p ; hsa-mir-610 ; hsa-mir-556-5p ; hsa-mir-499b-3p ; hsa-mir-499a-3p ; hsa-mir-4480 ; hsa-mir-6845-3p ; hsa-mir-1226-3p ; hsa-mir-512-3p ; hsa-mir-216b-5p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-548c-3p ; hsa-mir-8485 ; hsa-mir-4540 ; hsa-mir-6758-3p ; hsa-mir-6891-3p ; hsa-mir-6072 ; hsa-mir-6838-3p ; hsa-mir-153-3p ; hsa-mir-4276 ; hsa-mir-4766-3p ; hsa-mir-152-3p ; hsa-mir-148b-3p ; hsa-mir-148a-3p ; hsa-mir-3908 ; hsa-mir-4703-5p ; hsa-mir-3942-5p ; hsa-mir-6727-3p ; hsa-mir-1281 ; hsa-mir-4763-3p ; hsa-mir-6836-5p ; hsa-mir-1207-5p ; hsa-mir-6132 ; hsa-mir-660-3p ; hsa-mir-5193 ; hsa-mir-3918 ; hsa-mir-1306-5p ; hsa-mir-6895-5p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-411-5p ; hsa-mir-3202 ; hsa-mir-4533
Nearest miRNA
hsa-mir-107/Upstream/342994; hsa-mir-202/Downstream/2310315;
Nearest TSS
ENST00000439456/Upstream/29180; ENST00000436932/Downstream/9657;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/112333, chr10-CpG: 46/Downstream/114534
Upstream sequence
ACCTCCAGGAGGAAAAACCTGAGAGGGAAGAGCAAGCACTCCGATTTTTAGATGGGAGGGCATGGGCTGAGTTGAACTGTGGTCCCCCAAAGATATGTCC
Downstream sequence
AACCTGCTttgcagatgtaattaaggtaagggtgttgagagaaggccatcctggattcaggtgggccctgaatccaatgacaagtctttacaaaatacag
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate