Basic Information
VIS ID
TVIS44031190
Fusion event
HTLV-1-GRAMD1B integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr11
Cytoband
q24.1
Reference genome
NCBI36/hg18
Start
122919860/123543942 (Hg38)
End
122919860/123543942 (Hg38)
Orient
-
Location type
Intronic
Target gene
GRAMD1B
miRNAs that regulate target gene
hsa-mir-1277-5p ; hsa-mir-3686 ; hsa-mir-6083 ; hsa-mir-190a-3p ; hsa-mir-601 ; hsa-mir-4778-5p ; hsa-mir-4742-3p ; hsa-mir-8076 ; hsa-mir-5011-5p ; hsa-mir-6873-3p ; hsa-mir-4436b-5p ; hsa-mir-6509-3p ; hsa-mir-1236-3p ; hsa-mir-6515-3p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-1273g-3p ; hsa-mir-181a-2-3p ; hsa-mir-99b-3p ; hsa-mir-99a-3p ; hsa-mir-2861 ; hsa-mir-1238-3p ; hsa-mir-670-3p ; hsa-mir-4279 ; hsa-mir-6881-3p ; hsa-mir-6749-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-2116-3p ; hsa-mir-877-3p ; hsa-mir-32-5p ; hsa-mir-92b-3p ; hsa-mir-92a-3p ; hsa-mir-1227-5p ; hsa-mir-128-1-5p ; hsa-mir-128-2-5p ; hsa-mir-2278 ; hsa-mir-4640-5p ; hsa-mir-4726-5p ; hsa-mir-4786-5p ; hsa-mir-6165 ; hsa-mir-6501-3p ; hsa-mir-6762-5p ; hsa-mir-6845-5p
Nearest miRNA
hsa-let-7a-2/Upstream/162430; hsa-mir-3167/Downstream/3444516;
Nearest TSS
ENST00000527297/Upstream/18120; ENST00000534764/Downstream/16320;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/112821, chr11-CpG: 27/Downstream/33443
Upstream sequence
gctttcatttacttgttgtctgtgactgctcttgccctatcacaacagagttcagtagttaggacagactgtgtggtctgcaaagcttaaagtatttact
Downstream sequence
gtccggccctttgcagaaaaagtttgccgaccTTGCTTTATATTGTTAGCAGTTGAATAATTCTGAGTTGTTTTTCCACAAGACTCATGGTGACTCATGG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate