Basic Information
VIS ID
TVIS44031200
Fusion event
HTLV-1-PHF21A integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr11
Cytoband
p11.2
Reference genome
NCBI36/hg18
Start
46093447/46115320 (Hg38)
End
46093447/46115320 (Hg38)
Orient
-
Location type
Intronic
Target gene
PHF21A
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-221-3p ; hsa-mir-548c-3p ; hsa-mir-7855-5p ; hsa-mir-216a-5p ; hsa-mir-129-5p ; hsa-mir-1909-3p ; hsa-mir-4270 ; hsa-mir-4441 ; hsa-mir-4468 ; hsa-mir-6081 ; hsa-mir-6132 ; hsa-mir-6722-3p ; hsa-mir-6754-5p ; hsa-mir-6836-5p ; hsa-mir-759
Nearest miRNA
hsa-mir-129-2/Upstream/423544; hsa-let-7a-2/Downstream/261082;
Nearest TSS
ENST00000527297/Upstream/23115; ENST00000528480/Downstream/1258;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/192098, chr11-CpG: 65/Downstream/4508
Upstream sequence
GCTTTAGAAGAGTCCAAAGGATGGCTGAACCTCACATATAATTTCTAAAAGCTTTGGAAGAGTTCACCATAATTTTAAGACTGAATTGAGGGACAAGTAA
Downstream sequence
TAGAAAAGTTATTCATAAAGTCTACTTCAACATTTTTACAAAAGATAACTATTCAAAAATTTAACACACATATAAGAATTATACGAAAGCCTACAAAATA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate