Basic Information
VIS ID
TVIS44031212
Fusion event
HTLV-1-CORO1C integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr12
Cytoband
q24.11
Reference genome
NCBI36/hg18
Start
107639167/108721262 (Hg38)
End
107639167/108721262 (Hg38)
Orient
+
Location type
Intronic
Target gene
CORO1C
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-375 ; hsa-mir-125a-5p ; hsa-mir-30a-5p ; hsa-mir-1301-3p ; hsa-mir-218-5p ; hsa-mir-6124 ; hsa-mir-651-3p ; hsa-mir-514b-3p ; hsa-mir-6079 ; hsa-mir-514a-3p ; hsa-mir-19b-2-5p ; hsa-mir-19b-1-5p ; hsa-mir-19a-5p ; hsa-mir-2052 ; hsa-mir-671-5p ; hsa-mir-6828-5p ; hsa-mir-4766-5p ; hsa-mir-146a-3p ; hsa-mir-6513-3p ; hsa-mir-4694-3p ; hsa-mir-6807-5p ; hsa-mir-203b-3p ; hsa-mir-7158-3p ; hsa-mir-6751-3p ; hsa-mir-1199-5p
Nearest miRNA
hsa-let-7i/Upstream/85392; hsa-mir-1178/Downstream/115646;
Nearest TSS
ENST00000382841/Upstream/18187; ENST00000548052/Downstream/9289;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/129211, chr12-CpG: 115/Downstream/9599
Upstream sequence
CCCACAAATTACACTTTCACCTACCTTTATAACTCCATAACCAAACTATATTTACATTTTACTCTAACATATTGTATAAATGCATAACCTATTATCATCA
Downstream sequence
CTTTCCATAATCAGGGCCATCTCATCTACCCATCTTACACTACTCTTCCCTAATTACACCAGTTCTGAGTCAGCCCAGTACTATTAGGCACACCCTCAGG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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