Basic Information
VIS ID
TVIS44031218
Fusion event
HTLV-1-FGD6 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr12
Cytoband
q22
Reference genome
NCBI36/hg18
Start
94134694/95216787 (Hg38)
End
94134694/95216787 (Hg38)
Orient
+
Location type
Intronic
Target gene
FGD6
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-98-5p ; hsa-mir-6807-5p ; hsa-mir-135b-3p ; hsa-mir-8077 ; hsa-mir-7160-5p ; hsa-mir-4663 ; hsa-mir-508-3p ; hsa-mir-5186 ; hsa-mir-186-3p ; hsa-mir-4698 ; hsa-mir-150-5p ; hsa-mir-8059 ; hsa-mir-4471 ; hsa-mir-1292-5p ; hsa-mir-6837-5p ; hsa-mir-4685-5p ; hsa-mir-3918 ; hsa-mir-802 ; hsa-mir-8083 ; hsa-mir-6753-5p ; hsa-mir-129-5p ; hsa-mir-8055 ; hsa-mir-4309 ; hsa-mir-3198 ; hsa-mir-4294 ; hsa-mir-1289 ; hsa-mir-8082 ; hsa-mir-4534 ; hsa-mir-1273f ; hsa-mir-4708-5p ; hsa-mir-6088 ; hsa-mir-4770 ; hsa-mir-143-3p ; hsa-mir-6514-5p ; hsa-mir-3692-3p ; hsa-mir-524-5p ; hsa-mir-520d-5p ; hsa-mir-8087 ; hsa-mir-7161-5p ; hsa-mir-548u
Nearest miRNA
hsa-let-7i/Upstream/382274; hsa-mir-1178/Downstream/91633;
Nearest TSS
ENST00000382841/Upstream/7831; ENST00000551792/Downstream/592;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/143099, chr12-CpG: 118/Downstream/271
Upstream sequence
aaaaCCTCAACAATCTCAACTCCTCTGCTTCTCAGGTAACAGAGGTAAAACCACCAGGACATGACAATGTCTACGCCTCTTTAAAATGGGTAAAAGGTTT
Downstream sequence
ACCAGCAGATACAAGGTTGAAAGCGACTCACTTAGTGGCCAAATTGAACACGCTGAGAACACTGCCTTTACCTATAATAACTGATCTATTAACTTGGGAA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate