Basic Information
VIS ID
TVIS44031243
Fusion event
HTLV-1-FLT3 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr13
Cytoband
q12.2
Reference genome
NCBI36/hg18
Start
27486708/28014571 (Hg38)
End
27486708/28014571 (Hg38)
Orient
-
Location type
Intronic
Target gene
FLT3
miRNAs that regulate target gene
hsa-mir-150-5p ; hsa-mir-335-5p
Nearest miRNA
hsa-mir-2276/Upstream/3852067; hsa-mir-1267/Downstream/11649463;
Nearest TSS
ENST00000623511/Upstream/59; ENST00000483842/Downstream/86021;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/33643, chr13-CpG: 118/Downstream/85519
Nearest cancer related gene
FLT3(TSG, No orient, 0)
Upstream sequence
GCTGACATCCTAAAAACGAAGTCAAATTAGGGAAGGATGGCCGTTTCCTTGAGTCAAAAGCCCAGCAGGATTGCATTATAATGTATCTGTAAAAGCAATA
Downstream sequence
GAACAAGGAACAAGATGAAGAAGTCTGAATGAAGCAAAATGGATCATTTTCCATATAATGAAGCACCATTTATTCCTCTGGAGCTGCTTATTTACAGCAT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate