Basic Information
VIS ID
TVIS44031286
Fusion event
HTLV-1-TJP1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr15
Cytoband
q13.1
Reference genome
NCBI36/hg18
Start
27908946/29829451 (Hg38)
End
27908946/29829451 (Hg38)
Orient
-
Location type
Intronic
Target gene
TJP1
miRNAs that regulate target gene
hsa-mir-212-3p ; hsa-mir-155-5p ; hsa-mir-615-3p ; hsa-mir-324-3p ; hsa-mir-17-5p ; hsa-let-7b-5p ; hsa-mir-105-5p ; hsa-mir-4799-5p ; hsa-mir-194-5p ; hsa-mir-383-3p ; hsa-mir-548c-3p ; hsa-mir-103a-3p ; hsa-mir-107 ; hsa-mir-379-3p ; hsa-mir-411-3p ; hsa-mir-802 ; hsa-mir-4801 ; hsa-mir-5700 ; hsa-mir-4731-3p ; hsa-mir-5582-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-212-5p ; hsa-mir-34c-5p
Nearest miRNA
hsa-mir-1268a/Upstream/1338606; hsa-mir-10393/Downstream/1235581;
Nearest TSS
ENST00000557528/Upstream/6820; ENST00000568123/Downstream/126843;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/6439, chr15-CpG: 97/Downstream/138841
Upstream sequence
TGTTACTTTCGAGCCTCTGGACTTTCATAAGCTTAGGTGTGCGAGGGTGCCTGGAGGAGGCAGAGAGCATAAATACAAAGTCACATAGAGGGTCCACGTG
Downstream sequence
GAGTTTCACATTTCTGATTCAGTTCAGGAAACTTTTTTCCTCATGCTCACCTTTATGAAAGAACTGCTGTGAGACATTTCTGAGCCTCAAACACTAAGGG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate