Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene197369602000934420319026199043021997834320008548200119991997650519979334199794281998065720008051200092341999269319993400199869681998735720027993
Basic Information
VIS ID
TVIS44031304
Fusion event
HTLV-1-SPECC1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr17
Cytoband
p11.2
Reference genome
NCBI36/hg18
Start
19871898/20027993 (Hg38)
End
19871898/20027993 (Hg38)
Orient
+
Location type
Intronic
Target gene
SPECC1
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-186-5p ; hsa-mir-10a-5p ; hsa-mir-3613-3p ; hsa-mir-3976 ; hsa-mir-5007-5p ; hsa-mir-4717-3p ; hsa-mir-6871-5p ; hsa-mir-449b-3p ; hsa-mir-5698 ; hsa-mir-377-3p ; hsa-mir-143-5p ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-3135b ; hsa-mir-6847-3p ; hsa-mir-6499-3p ; hsa-mir-103b ; hsa-mir-4438 ; hsa-mir-6768-5p
Nearest miRNA
hsa-mir-1180/Upstream/683419; hsa-mir-10226/Downstream/7265917;
Nearest TSS
ENST00000595228/Upstream/10848; ENST00000580934/Downstream/45572;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/17897, chr17-CpG: 117/Downstream/127722
Upstream sequence
ttccagcacaaaggtttttcattttggtaggtacaatttaccctattttaccttagttggtcatgcttttggtgtcatgtctaagaattctttgtcaaac
Downstream sequence
ctaacgtctttaagatttacccgtatgtttccttctaagagttttacagtcgtaactcttacgtttaagtcatcaattcatttttgaattaatttttgca
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate