Basic Information
VIS ID
TVIS44031312
Fusion event
HTLV-1-INO80C integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr18
Cytoband
q12.2
Reference genome
NCBI36/hg18
Start
31318009/35484047 (Hg38)
End
31318009/35484047 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA18A
Target gene
INO80C
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-9-3p ; hsa-mir-548as-3p ; hsa-mir-543 ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-510-3p ; hsa-mir-3692-3p ; hsa-mir-4436b-5p ; hsa-mir-6509-3p ; hsa-mir-494-3p
Nearest miRNA
hsa-mir-1-2/Upstream/5185087; hsa-mir-122/Downstream/107690;
Nearest TSS
ENST00000575820/Upstream/16959; ENST00000586725/Downstream/3423;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/106605, chr18-CpG: 53/Downstream/13534
Upstream sequence
aggatgcggcaggggataaaaaatagaattttaaaaaccctgtaaacacaaattcacttgtgtttcaaataacataaccacactgaagtggaggcaaggg
Downstream sequence
agaaataacctgagtaactatgaatatggtattttgactatgtaatccaaggttaaaggccaaaaagaaccatacatagttggtaagtttgtttctcaca
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate