Basic Information
VIS ID
TVIS44031319
Fusion event
HTLV-1-DYM integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr18
Cytoband
q21.1
Reference genome
NCBI36/hg18
Start
45194124/49413756 (Hg38)
End
45194124/49413756 (Hg38)
Orient
-
Location type
Intronic
Target gene
DYM
miRNAs that regulate target gene
hsa-mir-941 ; hsa-mir-129-5p ; hsa-mir-3680-3p ; hsa-mir-557 ; hsa-mir-507 ; hsa-mir-450b-5p ; hsa-mir-1238-3p ; hsa-mir-670-3p ; hsa-mir-106a-3p ; hsa-mir-6749-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-223-5p ; hsa-mir-6832-3p ; hsa-mir-6756-3p ; hsa-mir-3127-3p
Nearest miRNA
hsa-mir-1-2/Upstream/363988; hsa-mir-122/Downstream/73617;
Nearest TSS
ENST00000575820/Upstream/624; ENST00000581232/Downstream/46871;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/437150, chr18-CpG: 74/Downstream/46378
Upstream sequence
caatgggtaattagtcagacttaaggaaggaaattacatcatggattatgaactttgaaggcattatactaggccaggcacagtggctcaagcctataat
Downstream sequence
cccagcactttgggaggccaaggcaggcagatcacttgaggtcaggagttcaagactagcctggccaacatggtgaaaccccgtctccactaaaaaatac
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate