Basic Information
VIS ID
TVIS44031327
Fusion event
HTLV-1-ZNF414 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr19
Cytoband
p13.2
Reference genome
NCBI36/hg18
Start
8483345/8512461 (Hg38)
End
8483345/8512461 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
ZNF414
Nearest miRNA
hsa-mir-1227/Upstream/123081; hsa-let-7e/Downstream/1525893;
Nearest TSS
ENST00000633603/Upstream/47; ENST00000598703/Downstream/1687;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/520, chr19-CpG: 62/Downstream/1316
Upstream sequence
GGAGCTCAAGAGGTCAGGGTCTCACTTGAAGTAGCGATTGGGTTTGTAGTGCAGTTTGCTGTGAGCCACCAGCTCCTGCATGCTGGGGAAGGTCTCGGTG
Downstream sequence
CAGCTCAGGGCTGAGCAGCGGAAGAGCTTGCCTGGTAGGGATGAAGGACAGAGAAGTGGAGACAGGTGGCCAAGGCTGGCTCCGAGGGGCTCCGCCTGTT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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