Basic Information
VIS ID
TVIS44031370
Fusion event
HTLV-1-COMMD10 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr5
Cytoband
q23.1
Reference genome
NCBI36/hg18
Start
115795844/116432248 (Hg38)
End
115795844/116432248 (Hg38)
Orient
+
Location type
Intronic
Target gene
COMMD10
miRNAs that regulate target gene
hsa-mir-16-5p
Nearest miRNA
hsa-mir-10397/Upstream/176414; hsa-mir-103a-1/Downstream/2542338;
Nearest TSS
ENST00000502646/Upstream/128114; ENST00000512128/Downstream/15299;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/70356, chr5-CpG: 27/Downstream/15131
Upstream sequence
TTTGAACCATCATATCTCATAAAAGGTTGCTTCACAGGCAATTTGAACAGCATTAAAAAAAAGCTTAATCTGCAGTTTGCTGCACGAATGAAGGCGATAC
Downstream sequence
ACCTTTATCGGAGGTTGAATGCTTCAGATTATATTTGCTGAAAATGGATAAGACTGTGCCATTATTTCTGAAGCATCTGTGAAATCAAATCTTGTTGTCT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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