Basic Information
VIS ID
TVIS44031373
Fusion event
HTLV-1-EPHA7 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr6
Cytoband
q16.1
Reference genome
NCBI36/hg18
Start
94174970/93408531 (Hg38)
End
94174970/93408531 (Hg38)
Orient
-
Location type
Intronic
Target gene
EPHA7
miRNAs that regulate target gene
hsa-mir-196a-5p ; hsa-mir-93-5p ; hsa-mir-455-3p ; hsa-mir-615-3p ; hsa-mir-331-3p ; hsa-mir-125b-5p ; hsa-mir-92a-3p ; hsa-mir-548c-3p ; hsa-mir-590-3p ; hsa-mir-8061 ; hsa-mir-4775 ; hsa-mir-4760-5p ; hsa-mir-3934-3p ; hsa-mir-4330 ; hsa-mir-10b-3p ; hsa-mir-577 ; hsa-mir-6757-3p ; hsa-mir-141-3p ; hsa-mir-200a-3p
Nearest miRNA
hsa-mir-10398/Upstream/1886794; hsa-mir-1202/Downstream/4616000;
Nearest TSS
ENST00000381078/Upstream/338144; ENST00000424678/Downstream/10995;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/2797031, chr6-CpG: 92/Downstream/8023
Upstream sequence
GCCTACAAGCAGGGATAAATCTTCATCAGTTTCTGATTTCCACATATATGGAAACTGCAGGATTTTCTACTCAATTAGAAATACTGCCAGTGAGGGAAAG
Downstream sequence
GGAAACAGGACAATAGGAGACAGGTTTGACTCCTTCAGGGACATAAAAGGAGACTGCTAAACTGGTCTATGGGACCTGAACCTATATCATCTCCATTTGT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate