Basic Information
VIS ID
TVIS44031377
Fusion event
HTLV-1-ARHGEF9 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chrX
Cytoband
q11.1
Reference genome
NCBI36/hg18
Start
62891426/63754821 (Hg38)
End
62891426/63754821 (Hg38)
Orient
+
Location type
Intronic
Target gene
ARHGEF9
miRNAs that regulate target gene
hsa-mir-574-5p ; hsa-mir-6867-5p ; hsa-mir-4711-3p ; hsa-mir-223-5p ; hsa-mir-297 ; hsa-mir-3177-5p ; hsa-mir-511-3p ; hsa-mir-567 ; hsa-mir-6817-3p ; hsa-mir-6873-3p ; hsa-mir-7110-3p
Nearest miRNA
hsa-let-7f-2/Upstream/8303239; hsa-mir-105-1/Downstream/31181;
Nearest TSS
ENST00000429181/Upstream/66; ENST00000617377/Downstream/211;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/403274, chrX-CpG: 43/Downstream/12
Upstream sequence
TTGGCGCCCGAGTTTAGTCGGGGGAGGGGAGGGGGATGGGGACGGGGTGCTTGGTTCCCCCCTTCTCAGGATTGGGCTGATCGTTTGTCCCTAGCTGAGA
Downstream sequence
AATCTTAGCTTGCGCTGAAGTCGGCAGAGTCCAGCATTCTCTCTCGGGCGCCACGGGAAAGGCAAAATCCTAGCTTTCAAAGGGAAAGGCGGGGGGAACC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate