Basic Information
VIS ID
TVIS44031378
Fusion event
HTLV-1-ARHGEF10 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr8
Cytoband
p23.3
Reference genome
NCBI36/hg18
Start
1887559/1951986 (Hg38)
End
1887559/1951986 (Hg38)
Orient
-
Location type
Intronic
Target gene
ARHGEF10
miRNAs that regulate target gene
hsa-mir-9-5p ; hsa-mir-192-5p
Nearest miRNA
hsa-mir-3674/Upstream/134679; hsa-mir-10400/Downstream/124603;
Nearest TSS
ENST00000518652/Upstream/8332; ENST00000605539/Downstream/19411;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/6069, chr8-CpG: 108/Downstream/21722
Upstream sequence
GTAACTGCAGTGAGGTGGGGTCTTCCTTGTAGCCACCGTGAGGCGGGGTCTTCCCTGTAACCGCCGTGAGGCGGGGTCTTGGAATAGGCCATGCGTCTCC
Downstream sequence
CACATTGTTTTGCAgccactttctagccttgtcactgccggagcaaattgtttagtttctctgggcttcagatccttggctgtaaagcaaatcaaaacca
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate