Basic Information
VIS ID
TVIS44031379
Fusion event
HTLV-1-LINGO2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr9
Cytoband
p21.1
Reference genome
NCBI36/hg18
Start
28886557/28896559 (Hg38)
End
28886557/28896559 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA9C
Target gene
LINGO2
miRNAs that regulate target gene
hsa-mir-587 ; hsa-mir-7162-5p ; hsa-mir-516b-3p ; hsa-mir-516a-3p ; hsa-mir-2115-5p ; hsa-mir-1976 ; hsa-mir-6893-3p ; hsa-mir-370-3p ; hsa-mir-660-3p ; hsa-mir-5193
Nearest miRNA
hsa-mir-101-2/Upstream/7604; hsa-let-7a-1/Downstream/4212133;
Nearest TSS
ENST00000422679/Upstream/226273; ENST00000541043/Downstream/1678453;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/1322570, chr9-CpG: 74/Downstream/315614
Upstream sequence
TGCACAAGCTAGAATATGAGCAAGAAATACATAATGAGAATGTTAGTATACACCTATGCAACAAGTTGCTTATAAACCTACACTGTTATCTCTATGTAAT
Downstream sequence
AGTGAAAATTTAGCTCTTTGTACTCAAATGCCATAAAAAAATAAGAATGAAGTAAAAAATGTATATAAAACCTTTGGCTAGAAGGCCATTTATTTTAGCA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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