Basic Information
VIS ID
TVIS44031385
Fusion event
HTLV-1-SPNS2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr17
Cytoband
p13.2
Reference genome
NCBI36/hg18
Start
4376174/4526130 (Hg38)
End
4376174/4526130 (Hg38)
Orient
+
Location type
Intronic
Target gene
SPNS2
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-3667-3p ; hsa-mir-6734-3p ; hsa-mir-6837-5p ; hsa-mir-4685-5p ; hsa-mir-8485 ; hsa-mir-7113-5p
Nearest miRNA
hsa-mir-1253/Upstream/1777948; hsa-mir-10226/Downstream/443572;
Nearest TSS
ENST00000595228/Upstream/26456; ENST00000573990/Downstream/6902;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/26102, chr17-CpG: 30/Downstream/9875
Upstream sequence
TTCAGGATAGCCCTGTCCTTGGGAGCACCCAGGCTTCGGGGTAGGAAGATTTGACAGGAACTCCTGTGTTCAGAGCCTTCAAGAGGTGTAGAAAAAGTGC
Downstream sequence
TGAGAGTCCTCACTAAAGAGACAACAGTCTCTTGAAATCCGtggggtcagggagggcttcctggaggaggtggcgtttgcgctgggCAGGCAGGACTGTG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate