Basic Information
VIS ID
TVIS44031405
Fusion event
HTLV-1-NCAPD2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr12
Cytoband
p13.31
Reference genome
NCBI36/hg18
Start
6473681/6494254 (Hg38)
End
6473681/6494254 (Hg38)
Orient
+
Location type
Intronic
Target gene
NCAPD2
miRNAs that regulate target gene
hsa-mir-193b-3p ; hsa-mir-155-5p ; hsa-mir-16-5p ; hsa-mir-1303 ; hsa-mir-93-3p ; hsa-mir-615-3p ; hsa-mir-92b-3p ; hsa-mir-484 ; hsa-mir-331-3p ; hsa-mir-186-5p ; hsa-mir-222-3p ; hsa-let-7b-5p ; hsa-mir-3620-3p ; hsa-mir-106b-5p ; hsa-mir-20a-5p ; hsa-mir-6807-5p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-3681-3p ; hsa-mir-216a-3p ; hsa-mir-128-3p ; hsa-mir-371b-3p ; hsa-mir-449b-3p ; hsa-mir-4438 ; hsa-mir-8070 ; hsa-mir-106a-3p ; hsa-mir-3650 ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-3135b ; hsa-mir-6741-3p ; hsa-mir-454-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-301b-3p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-130a-3p ; hsa-mir-320e ; hsa-mir-519d-3p ; hsa-mir-93-5p ; hsa-mir-17-5p ; hsa-mir-20b-5p
Nearest miRNA
hsa-mir-3649/Upstream/4833874; hsa-let-7i/Downstream/469445;
Nearest TSS
ENST00000382841/Upstream/155; ENST00000545732/Downstream/16971;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/114, chr12-CpG: 123/Downstream/39841
Upstream sequence
GTAAGATGTGGTGTTGCAGGTCGTAAAAGAGTAGGAAAGTCGAGTACATGGCAGTGTGACCCAGTCTTGGGCAAAATACAATAGGCCTAGTAAGTATATC
Downstream sequence
CCTGGGGCGCGATGTGTGAGAAACTGTAAGTCTGACAGATCCGCAACGGAAGTTGTTAAGCAAATCGCTTAACAGATCCGCAACGGAAGATGTTAAGCAA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate