Basic Information
VIS ID
TVIS44031425
Fusion event
HTLV-1-SLC25A21 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr14
Cytoband
q13.3
Reference genome
NCBI36/hg18
Start
36597929/37058973 (Hg38)
End
36597929/37058973 (Hg38)
Orient
-
Location type
Intronic
Target gene
SLC25A21
miRNAs that regulate target gene
hsa-mir-625-5p ; hsa-mir-4668-5p ; hsa-mir-3148 ; hsa-mir-335-3p ; hsa-mir-3611 ; hsa-mir-4289 ; hsa-mir-4666a-3p
Nearest miRNA
hsa-mir-208a/Upstream/106582; hsa-mir-1185-1/Downstream/10702022;
Nearest TSS
ENST00000550708/Upstream/250102; ENST00000556667/Downstream/112915;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/391830, chr14-CpG: 61/Downstream/113054
Upstream sequence
GGATCAGATGAACATAAGTGGCATCTGAACTGATGGTCACCCCTTCCCTCTGCCTCAAACTCCTCCCTTAAGAAAGGTTAAGAATCTCCATGAAGACTTC
Downstream sequence
CATGTCCTTTCCAGGTAGGAATCCCTTTTTCTCTGGCTACTATTCTAACTTAAATGCACCTATTGTTACACCATAATTATTCAAGTATCTTTTCTTATTT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate