Basic Information
VIS ID
TVIS44031435
Fusion event
HTLV-1-UNC13C integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr15
Cytoband
q21.3
Reference genome
NCBI36/hg18
Start
52343632/54264142 (Hg38)
End
52343632/54264142 (Hg38)
Orient
+
Location type
Intronic
Target gene
UNC13C
miRNAs that regulate target gene
hsa-mir-128-3p
Nearest miRNA
hsa-mir-10393/Upstream/1986942; hsa-mir-11181/Downstream/1108798;
Nearest TSS
ENST00000557528/Upstream/251238; ENST00000561210/Downstream/3;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/504335, chr15-CpG: 52/Downstream/932402
Upstream sequence
GCCACCTGACTCCACAGAATGAAAGCACTCATTCATTCTCACTTCCTCCTCCTTTTCCTCCCTCCTTTAGCCATCAAAAAGTAATGGCATTTCCATTCAC
Downstream sequence
ATCACCATTGATGTTTCCATCATAGGAGCAGCAGAAAAGAGTTCTAAACATGGTGCCGAAGACAAGACTCAGACCATTATTACAGCAATGAAAGAAAGAA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate