Basic Information
VIS ID
TVIS44031439
Fusion event
HTLV-1-CALN1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr7
Cytoband
q11.22
Reference genome
NCBI36/hg18
Start
70986793/71883872 (Hg38)
End
70986793/71883872 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA7J
Target gene
CALN1
miRNAs that regulate target gene
hsa-mir-148b-3p ; hsa-mir-675-5p ; hsa-mir-4635 ; hsa-mir-6849-3p ; hsa-mir-596 ; hsa-mir-634 ; hsa-mir-4520-2-3p ; hsa-mir-3692-3p ; hsa-mir-4520-3p ; hsa-mir-4436b-5p ; hsa-mir-6509-3p ; hsa-mir-3614-5p ; hsa-mir-890 ; hsa-mir-212-3p ; hsa-mir-132-3p ; hsa-mir-6754-3p ; hsa-mir-412-3p ; hsa-mir-6756-3p ; hsa-mir-3127-3p ; hsa-mir-7153-3p ; hsa-mir-137
Nearest miRNA
hsa-mir-1183/Upstream/576102; hsa-mir-10399/Downstream/814031;
Nearest TSS
ENST00000635602/Upstream/73377; ENST00000434423/Downstream/453123;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/750476, chr7-CpG: 187/Downstream/451900
Upstream sequence
tggtatataatcgctgggtcttgagggtattggcatgagatttaccatcttgtttcaccgctgcccaagacacatacatggcttctatttatatgtctcc
Downstream sequence
attaaatgtttcctcctgagaaactggatatatcagcctctttccttccttcctttctttctttgacagagtctctctgttgccaggttggagtgaagtg
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate