Basic Information
VIS ID
TVIS44031448
Fusion event
HTLV-1-FOXL2NB integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr3
Cytoband
q22.3
Reference genome
NCBI36/hg18
Start
140149856/138948324 (Hg38)
End
140149856/138948324 (Hg38)
Orient
+
Location type
Intronic
Target gene
FOXL2NB
miRNAs that regulate target gene
hsa-mir-1206 ; hsa-mir-1273g-3p ; hsa-mir-196a-3p ; hsa-mir-3664-5p ; hsa-mir-3672 ; hsa-mir-4252 ; hsa-mir-4522 ; hsa-mir-4793-3p ; hsa-mir-4797-5p ; hsa-mir-508-5p ; hsa-mir-5586-3p ; hsa-mir-6510-3p ; hsa-mir-6512-3p ; hsa-mir-661 ; hsa-mir-6720-5p ; hsa-mir-6849-3p ; hsa-mir-6864-3p ; hsa-mir-759 ; hsa-mir-766-3p ; hsa-mir-7703 ; hsa-mir-873-3p ; hsa-mir-939-3p ; hsa-mir-329-3p ; hsa-mir-362-3p ; hsa-mir-3941 ; hsa-mir-454-5p ; hsa-mir-4789-3p ; hsa-mir-603 ; hsa-mir-8485
Nearest miRNA
hsa-let-7g/Upstream/4510418; hsa-mir-1224/Downstream/12617552;
Nearest TSS
ENST00000440867/Upstream/712; ENST00000418282/Downstream/57482;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/759, chr3-CpG: 67/Downstream/1469
Upstream sequence
CAGACTGGGAAGACAAACATCAGGCTGAGGGAGGGACTTGTTCAAATCTCTCTCCTGATGAGACATTTGTTCTGATCTTTCTCCAAAGAATCAGGAGTTA
Downstream sequence
GTTGTCACCTACCTTAAGCAGAATTCTGATGGGAATCCAATTATTTCAGCATGTACAGAGATTGTTTCAGGGAAAATCAGGTGTGCCTTTTAACAGTGTG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate