Basic Information
VIS ID
TVIS44031456
Fusion event
HTLV-1-MEMO1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr2
Cytoband
p22.3
Reference genome
NCBI36/hg18
Start
32000467/31921894 (Hg38)
End
32000467/31921894 (Hg38)
Orient
+
Location type
Intronic
Target gene
MEMO1
miRNAs that regulate target gene
hsa-mir-4642 ; hsa-mir-580-3p ; hsa-mir-143-5p ; hsa-mir-3944-5p ; hsa-mir-3649 ; hsa-mir-5787 ; hsa-mir-4505 ; hsa-mir-657 ; hsa-mir-3665 ; hsa-mir-645 ; hsa-mir-4442 ; hsa-mir-3687 ; hsa-mir-4712-3p ; hsa-mir-6865-5p ; hsa-mir-6815-5p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-4797-5p ; hsa-mir-3929 ; hsa-mir-324-5p ; hsa-mir-129-5p ; hsa-mir-548ah-5p ; hsa-mir-3609 ; hsa-mir-4477a ; hsa-mir-2115-5p
Nearest miRNA
hsa-mir-1301/Upstream/3925445; hsa-mir-10b/Downstream/610259;
Nearest TSS
ENST00000437798/Upstream/68471; ENST00000605811/Downstream/21489;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/340181, chr2-CpG: 174/Downstream/87690
Upstream sequence
AGCTTTCTCTATTCCCATTCAAGTAGAAGTCATTCTCAAAAACAAAGAAACTAGATTATGTGTTATTTGCACTGTAGTCTAAAGAAAAGAACTGAGCTAA
Downstream sequence
AGTGTAGCTTAAATCTTTACAATCTCTTTATCTTGACATCAAGAGTAATGTTAATTTCCTCTCATTCTGTCAAATACCCAAACCTGCCCTACAATCTGAA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate