Basic Information
VIS ID
TVIS44031457
Fusion event
HTLV-1-STX3 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr11
Cytoband
q12.1
Reference genome
NCBI36/hg18
Start
59292829/59768780 (Hg38)
End
59292829/59768780 (Hg38)
Orient
+
Location type
Intronic
Target gene
STX3
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-92a-3p ; hsa-let-7a-5p ; hsa-let-7b-5p ; hsa-let-7c-5p ; hsa-let-7d-5p ; hsa-let-7e-5p ; hsa-let-7f-5p ; hsa-let-7g-5p ; hsa-let-7i-5p ; hsa-mir-125b-2-3p ; hsa-mir-1273h-5p ; hsa-mir-202-3p ; hsa-mir-3065-3p ; hsa-mir-30b-3p ; hsa-mir-30c-1-3p ; hsa-mir-30c-2-3p ; hsa-mir-3120-3p ; hsa-mir-3145-5p ; hsa-mir-3189-3p ; hsa-mir-335-5p ; hsa-mir-342-3p ; hsa-mir-3689a-3p ; hsa-mir-3689b-3p ; hsa-mir-3689c ; hsa-mir-3927-3p ; hsa-mir-4457 ; hsa-mir-4458 ; hsa-mir-4500 ; hsa-mir-4650-3p ; hsa-mir-5007-5p ; hsa-mir-508-5p ; hsa-mir-513b-5p ; hsa-mir-5192 ; hsa-mir-519a-3p ; hsa-mir-519b-3p ; hsa-mir-519c-3p ; hsa-mir-6731-5p ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-6788-5p ; hsa-mir-6813-3p ; hsa-mir-6814-5p ; hsa-mir-6831-5p ; hsa-mir-6878-5p ; hsa-mir-8085 ; hsa-mir-887-5p ; hsa-mir-98-5p
Nearest miRNA
hsa-mir-129-2/Upstream/173622; hsa-let-7a-2/Downstream/440291;
Nearest TSS
ENST00000527297/Upstream/13321; ENST00000528805/Downstream/18287;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/13126, chr11-CpG: 32/Downstream/41837
Upstream sequence
ATGACAGACAGGCTGAGGACTTTTATACAGTAAGTAATAGGGAACCATCATGTATTGGGAAACAGGGACATAATGGGATTGGACCAGAGAGATAATGGAG
Downstream sequence
GTGGGTATGGGCAGGAGACTGTTGTAATGGTACAGGGTCTGCTACTCAAGCAAGGTCCAAaaatactctattattactattttatagatgaggaaattga
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate