Basic Information
VIS ID
TVIS44031461
Fusion event
HTLV-1-PHF14 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr7
Cytoband
p21.3
Reference genome
NCBI36/hg18
Start
10988477/10982325 (Hg38)
End
10988477/10982325 (Hg38)
Orient
+
Location type
Intronic
Target gene
PHF14
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-128-3p ; hsa-mir-122-5p ; hsa-mir-183-5p ; hsa-mir-5585-3p ; hsa-mir-4474-5p ; hsa-mir-4635 ; hsa-mir-3613-3p ; hsa-mir-429 ; hsa-mir-200c-3p ; hsa-mir-200b-3p
Nearest miRNA
hsa-mir-339/Upstream/3915280; hsa-mir-10399/Downstream/7144895;
Nearest TSS
ENST00000635602/Upstream/8418; ENST00000476774/Downstream/31496;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/8064, chr7-CpG: 25/Downstream/849456
Upstream sequence
TGTCTACCATTCTTTGACTTAAATTTGTTTATATTGTTTTGCAAGTTATTCACAAATTTTGGTGGTTTCATTTGTGTCAGCGTtgtgtgtgtgtgtgtgt
Downstream sequence
atgtatatacatatgtgtgGTTTTTTTTTTCTCATATTTTCAACAGATTCTGAAGGGAGTGGTAATGGAAGTGAAGATGCTTCAAAGGACAGTGGAGAAG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate