Basic Information
VIS ID
TVIS44031487
Fusion event
HTLV-1-TRIM44 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr11
Cytoband
p13
Reference genome
NCBI36/hg18
Start
35658855/35680731 (Hg38)
End
35658855/35680731 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA11E
Target gene
TRIM44
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-16-5p ; hsa-mir-484 ; hsa-mir-222-3p ; hsa-mir-17-5p ; hsa-mir-6803-5p ; hsa-mir-6751-5p ; hsa-mir-4674 ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-4764-3p ; hsa-mir-3177-5p ; hsa-mir-4417 ; hsa-mir-654-5p ; hsa-mir-541-3p ; hsa-mir-6766-5p ; hsa-mir-6756-5p ; hsa-mir-608 ; hsa-mir-4651 ; hsa-mir-7110-5p ; hsa-mir-6842-5p ; hsa-mir-6752-5p ; hsa-mir-6835-5p ; hsa-mir-4437 ; hsa-mir-637 ; hsa-mir-6742-3p ; hsa-mir-6852-5p ; hsa-mir-939-3p ; hsa-mir-545-3p ; hsa-mir-511-3p ; hsa-mir-3908 ; hsa-mir-7111-5p ; hsa-mir-6870-5p ; hsa-mir-5698 ; hsa-mir-4723-5p ; hsa-mir-939-5p ; hsa-mir-6883-5p ; hsa-mir-1343-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-6827-5p ; hsa-mir-4539 ; hsa-mir-6794-5p ; hsa-mir-4716-3p ; hsa-mir-4756-5p ; hsa-mir-4739 ; hsa-mir-4293 ; hsa-mir-1321 ; hsa-mir-4762-3p ; hsa-mir-3192-3p ; hsa-mir-2115-5p ; hsa-mir-5009-3p ; hsa-mir-381-3p ; hsa-mir-300 ; hsa-mir-4668-3p ; hsa-mir-552-5p ; hsa-mir-302c-5p ; hsa-mir-6826-3p ; hsa-mir-6795-3p ; hsa-mir-6887-3p ; hsa-mir-5685 ; hsa-mir-4690-3p ; hsa-mir-4323 ; hsa-mir-3591-3p ; hsa-mir-21-3p
Nearest miRNA
hsa-mir-1343/Upstream/738811; hsa-let-7a-2/Downstream/329367;
Nearest TSS
ENST00000527297/Upstream/17926; ENST00000532066/Downstream/43525;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/17377, chr11-CpG: 80/Downstream/263335
Upstream sequence
tacttttgtacatgcatccttgacacaggtgcTAGTCTTCCTCAAGAGGAAAGGAGAAGTGGATTGGTAGGCATGTGAtttcagagtggcagttatttta
Downstream sequence
tatatccatcaacaacatatggaagtccccaatttccccagggcctaacacttgctgttatGAGATTAAAATTTATTTCAGGCTGATGGGTAAGAAATTA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate