Basic Information
VIS ID
TVIS44031493
Fusion event
HTLV-1-KCNA4 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr11
Cytoband
p14.1
Reference genome
NCBI36/hg18
Start
29992506/30014383 (Hg38)
End
29992506/30014383 (Hg38)
Orient
-
Location type
Intronic
Target gene
KCNA4
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-377-3p ; hsa-mir-4789-5p ; hsa-mir-3682-5p ; hsa-mir-3941 ; hsa-mir-4789-3p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485
Nearest miRNA
hsa-mir-210/Upstream/1536835; hsa-let-7a-2/Downstream/4927454;
Nearest TSS
ENST00000527297/Upstream/31991; ENST00000533718/Downstream/1976;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/1903709, chr11-CpG: 25/Downstream/1742
Upstream sequence
GCACTGCCTGACTCCCTACAGCATGTCCCCATTGTTTTTCTGTTCCCTTGAATCCTGAACACTCCCTACCACCCACAGACTAGGAACTAATGCCAATTTC
Downstream sequence
CACATCTCTAATAACCATCTTCTCTCCTTGGCGGTCACTCCATGTTCACCTCAATGGTTCCTCCTCCACTCTGCTCAAGGGACTATCTCCTTATTTTTTT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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