Basic Information
VIS ID
TVIS44031494
Fusion event
HTLV-1-ATP2B1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr12
Cytoband
q21.33
Reference genome
NCBI36/hg18
Start
88543850/89625942 (Hg38)
End
88543850/89625942 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA12B
Target gene
ATP2B1
miRNAs that regulate target gene
hsa-mir-204-5p ; hsa-mir-615-3p ; hsa-let-7a-5p ; hsa-mir-150-5p ; hsa-mir-4713-5p ; hsa-mir-6892-3p ; hsa-mir-6817-3p ; hsa-mir-6873-3p ; hsa-mir-7110-3p ; hsa-mir-20a-5p ; hsa-mir-106b-5p ; hsa-mir-142-3p ; hsa-mir-4465 ; hsa-mir-498 ; hsa-mir-26b-5p ; hsa-mir-26a-5p ; hsa-mir-1297 ; hsa-mir-5697 ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-4282 ; hsa-mir-3606-3p ; hsa-mir-6749-3p ; hsa-mir-642a-5p ; hsa-mir-6845-3p ; hsa-mir-4469 ; hsa-mir-2116-3p ; hsa-mir-532-3p ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-2276-5p ; hsa-mir-483-3p ; hsa-mir-181d-5p ; hsa-mir-181c-5p ; hsa-mir-181b-5p ; hsa-mir-519d-3p ; hsa-mir-181a-5p ; hsa-mir-93-5p ; hsa-mir-20b-5p ; hsa-mir-17-5p
Nearest miRNA
hsa-let-7i/Upstream/2880793; hsa-mir-1178/Downstream/4935847;
Nearest TSS
ENST00000382841/Upstream/13795; ENST00000605386/Downstream/4812;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/99815, chr12-CpG: 258/Downstream/81717
Upstream sequence
AGTAAAATGATGCAATTTAAGCAATTTTAATAATATATGCTTATTTATCCACACAGTGTTCTTCCAAAAAGATGCTACCGCTGGAGGTCATGCTGTTTCT
Downstream sequence
AACCTCAGAGCTCTGCTTTTTCCCTTAAAGAATGGCTGTATTAACAGGTATTTTCTAGTGATGGCAGTAATATAGAAACTTCAGCCGCACTACAACGACT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate