Basic Information
VIS ID
TVIS44031503
Fusion event
HTLV-1-RPRD1A integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr18
Cytoband
q12.2
Reference genome
NCBI36/hg18
Start
31833127/35999166 (Hg38)
End
31833127/35999166 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA18A
Target gene
RPRD1A
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-30a-5p ; hsa-mir-181b-5p ; hsa-mir-10a-5p ; hsa-mir-20a-5p ; hsa-mir-140-3p ; hsa-mir-1911-5p ; hsa-mir-4461 ; hsa-mir-4804-3p ; hsa-mir-6869-5p
Nearest miRNA
hsa-mir-1-2/Upstream/65024; hsa-mir-122/Downstream/1657969;
Nearest TSS
ENST00000575820/Upstream/5866; ENST00000541190/Downstream/29024;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/26177, chr18-CpG: 65/Downstream/67936
Upstream sequence
AACTTCCTATGATATACTACTATACAAGTTATTTCTGAATTACTACTGGATTGTTTTCTAATTTCATACCCATAATTAGAAAACACACTTTCTATATATC
Downstream sequence
TACATTACTTGCAGTGTCCAGCAGGGGACTGAGTATTAACAGTACGCCCCAGTCAACACTCCATGAagtcagatctggatggagtactgtttcctcaatc
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate