Basic Information
VIS ID
TVIS44031504
Fusion event
HTLV-1-TCF12 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr15
Cytoband
q21.3
Reference genome
NCBI36/hg18
Start
55148773/57069283 (Hg38)
End
55148773/57069283 (Hg38)
Orient
+
Location type
Intronic
Target gene
TCF12
miRNAs that regulate target gene
hsa-mir-204-5p ; hsa-mir-211-5p ; hsa-mir-375 ; hsa-mir-155-5p ; hsa-mir-26b-5p ; hsa-mir-1224-3p ; hsa-mir-548v ; hsa-mir-33a-3p ; hsa-mir-139-5p ; hsa-mir-8485
Nearest miRNA
hsa-mir-10393/Upstream/1696249; hsa-mir-11181/Downstream/2101900;
Nearest TSS
ENST00000557528/Upstream/5535; ENST00000559216/Downstream/39975;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/149476, chr15-CpG: 58/Downstream/237057
Upstream sequence
CTAAGATACAGAGTTGGTCATTCCTTAGTTTAAAAGATAGAATTGAGTTCACTGATAGGAAACCACTGATAGGAATTACATTTATAGGCATCATCAGTGA
Downstream sequence
TCAAGAGTTGGCATTTTAATCATGAACATTTTTCAGTTTATATGTAATCTATTATGGTAGTTATTTTTTTAAAAAAGAAGCAATATTAAGTTGAGTAGAG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate