Basic Information
VIS ID
TVIS44031521
Fusion event
HTLV-1-NOL7 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr6
Cytoband
p23
Reference genome
NCBI36/hg18
Start
13724084/13615873 (Hg38)
End
13724084/13615873 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA6A
Target gene
NOL7
miRNAs that regulate target gene
hsa-mir-484
Nearest miRNA
hsa-mir-3691/Upstream/3176079; hsa-mir-10398/Downstream/2525683;
Nearest TSS
ENST00000381078/Upstream/284; ENST00000607518/Downstream/16882;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/202, chr6-CpG: 217/Downstream/94874
Nearest cancer related gene
NOL7(TSG, No orient, 0)
Upstream sequence
TTAGAGGCTAGGGAGGAGGTGTCTTATTAAAACAACTCGGCTCAGGGAGAATTCCTATGGTGGATGTAATTTGGGTTGGCAGGATATTGGAGTGGGGAAA
Downstream sequence
CAGTCACCAAGATTGCCTCTGACAGTGGTGGAAAGATGCTCGGGCCGGGCGCGGCAGTACTTTAGTTGGACGAGGTGGGCGgagcccgggatgtcgaggc
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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