Basic Information
VIS ID
TVIS44031527
Fusion event
HTLV-1-NRXN3 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr14
Cytoband
q24.3
Reference genome
NCBI36/hg18
Start
78035479/78499383 (Hg38)
End
78035479/78499383 (Hg38)
Orient
+
Location type
Intronic
Target gene
NRXN3
miRNAs that regulate target gene
hsa-mir-374b-5p ; hsa-mir-92a-3p ; hsa-mir-525-5p ; hsa-mir-520a-5p ; hsa-mir-6880-5p ; hsa-mir-3165 ; hsa-mir-8071 ; hsa-mir-505-5p ; hsa-mir-4795-5p ; hsa-mir-192-3p ; hsa-mir-5189-3p ; hsa-mir-4786-5p ; hsa-mir-1915-5p ; hsa-mir-3667-3p ; hsa-mir-6849-3p ; hsa-mir-665 ; hsa-mir-1304-5p ; hsa-mir-7160-5p ; hsa-mir-4722-5p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-1827 ; hsa-mir-4649-3p ; hsa-mir-3664-3p ; hsa-mir-1282 ; hsa-mir-5707 ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-4478 ; hsa-mir-3929 ; hsa-mir-4419b ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-4695-5p ; hsa-mir-510-5p ; hsa-mir-512-5p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-655-5p ; hsa-mir-5690 ; hsa-mir-7703 ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-1227-3p ; hsa-mir-1273a ; hsa-mir-4252 ; hsa-mir-4793-3p ; hsa-mir-766-3p ; hsa-mir-1273g-3p ; hsa-mir-3940-3p ; hsa-mir-508-5p ; hsa-mir-6516-5p ; hsa-mir-455-3p ; hsa-mir-6807-5p ; hsa-mir-6499-3p ; hsa-mir-2467-3p ; hsa-mir-4257 ; hsa-mir-6511a-5p ; hsa-mir-1910-3p
Nearest miRNA
hsa-mir-1260a/Upstream/1233093; hsa-mir-1185-1/Downstream/15448843;
Nearest TSS
ENST00000550708/Upstream/95633; ENST00000557081/Downstream/115549;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/518002, chr14-CpG: 66/Downstream/779427
Upstream sequence
cttTCACATGGGTCATTAAAGTCCGTCTGTAAAGTCTCAGGGACTTTCTCATCATTTTCCCTAAACCTAATGCAAGATATTCACATTTCTTTTTGTGCAA
Downstream sequence
AGAACAATCTTAATTCAGCTGATAATCGGGGCCTCCCTTACCTTCCCACTGCTCACTATAACAGAGAACAAGTACTAGCTCATAACTTTTTATGACTTTG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate