Basic Information
VIS ID
TVIS44031567
Fusion event
HTLV-1-POLA1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chrX
Cytoband
p22.11
Reference genome
NCBI36/hg18
Start
24661592/24733554 (Hg38)
End
24661592/24733554 (Hg38)
Orient
+
Location type
Intronic
Target gene
POLA1
miRNAs that regulate target gene
hsa-mir-193b-3p ; hsa-mir-124-3p ; hsa-mir-26b-5p ; hsa-mir-6885-3p ; hsa-mir-6882-3p
Nearest miRNA
hsa-mir-23c/Upstream/4716367; hsa-let-7f-2/Downstream/3762001;
Nearest TSS
ENST00000429181/Upstream/6621; ENST00000480125/Downstream/11949;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/39387, chrX-CpG: 290/Downstream/268566
Upstream sequence
TGGTGGTGGTGGGATTTCCTTTGAGGAAGACTGCTAAAATCTTCCATTCTGGCTTCAGTGGATAGATAGCAAATGTTTCATCAAAGCAGTTTTAACAACT
Downstream sequence
GCAGGGACTTAGGGTTCTGTGCTTGACCATTCTTTTGAGGTCATCAACATGACCAGTGGAAGTATTTGATGACCCTCCTAATTCTTTAGGGTTGGGGGGA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate