Basic Information
VIS ID
TVIS44031589
Fusion event
HTLV-1-AEBP2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr12
Cytoband
p12.3
Reference genome
NCBI36/hg18
Start
19482308/19438107 (Hg38)
End
19482308/19438107 (Hg38)
Orient
-
Location type
Intronic
Target gene
AEBP2
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-103a-3p ; hsa-mir-101-3p ; hsa-mir-484 ; hsa-mir-328-3p ; hsa-let-7e-5p ; hsa-mir-3686 ; hsa-mir-4775 ; hsa-mir-3607-3p ; hsa-mir-4778-5p ; hsa-mir-5580-3p ; hsa-mir-590-3p
Nearest miRNA
hsa-mir-1244-3/Upstream/1764713; hsa-let-7i/Downstream/4774314;
Nearest TSS
ENST00000382841/Upstream/34041; ENST00000360995/Downstream/1567;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/131336, chr12-CpG: 147/Downstream/1142
Upstream sequence
aatgtgggctcttttccagtctcctttcttccaatgacctcttccctactttacaaaagaaaggcataattcttcctcatgctaaatcttagtaaggtgc
Downstream sequence
aatacccggttatgcaaaaacctccaggacaccaaagaaaggcacaattGACTGgtgaataagaatggggtaacacatcctttcacaagtcaggtggttt
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate