Basic Information
VIS ID
TVIS44031598
Fusion event
HTLV-1-ADAMTSL1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr9
Cytoband
p22.1
Reference genome
NCBI36/hg18
Start
18722277/18732279 (Hg38)
End
18722277/18732279 (Hg38)
Orient
+
Location type
Intronic
Target gene
ADAMTSL1
miRNAs that regulate target gene
hsa-mir-132-3p ; hsa-mir-25-3p ; hsa-mir-3202 ; hsa-mir-3689d ; hsa-mir-377-5p ; hsa-mir-4533 ; hsa-mir-6079 ; hsa-mir-6086 ; hsa-mir-6133 ; hsa-mir-6134 ; hsa-mir-6851-5p ; hsa-mir-6880-5p ; hsa-mir-6894-5p ; hsa-mir-7154-3p ; hsa-mir-765 ; hsa-mir-766-5p ; hsa-mir-7847-3p
Nearest miRNA
hsa-mir-101-2/Upstream/158900; hsa-let-7a-1/Downstream/1678869;
Nearest TSS
ENST00000422679/Upstream/25638; ENST00000496521/Downstream/60946;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/293475, chr9-CpG: 79/Downstream/44481
Upstream sequence
GATATAGACCTTCATAATAATTTTATACTCACCGAGTTTATTCTGAAATTTTCTTAACCCACTAGTATGGGGCAGGGTAAAGCGAAGCTATGGATAGAAC
Downstream sequence
CTAGCTTCAAGCCAGCTTTCTGTACAGCCCTCACCAGATCTCTTAGGCAGTTAGACAACAGGAAGCAGGGCAGCTTGTCATCATGGGGTCCTGAAAAAGG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate