Basic Information
VIS ID
TVIS44031611
Fusion event
HTLV-1-SOX5 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr12
Cytoband
p12.1
Reference genome
NCBI36/hg18
Start
23849655/23805454 (Hg38)
End
23849655/23805454 (Hg38)
Orient
+
Location type
Intronic
Target gene
SOX5
miRNAs that regulate target gene
hsa-mir-21-5p ; hsa-mir-194-5p ; hsa-mir-335-5p ; hsa-mir-1-3p ; hsa-mir-26b-5p ; hsa-mir-96-5p ; hsa-mir-130a-3p ; hsa-mir-181a-5p ; hsa-mir-132-3p ; hsa-mir-15a-5p ; hsa-mir-16-5p ; hsa-mir-1231 ; hsa-mir-632 ; hsa-mir-4288 ; hsa-mir-548s ; hsa-mir-3926 ; hsa-mir-4766-5p ; hsa-mir-1277-5p ; hsa-mir-3924 ; hsa-mir-190a-3p ; hsa-mir-6867-5p ; hsa-mir-223-5p ; hsa-mir-511-3p ; hsa-mir-5011-5p ; hsa-mir-574-5p ; hsa-mir-5580-3p ; hsa-mir-555 ; hsa-mir-374a-3p ; hsa-mir-136-3p ; hsa-mir-4704-5p ; hsa-mir-3529-3p ; hsa-mir-6759-5p ; hsa-mir-6793-5p ; hsa-mir-6748-5p ; hsa-mir-933 ; hsa-mir-4783-5p ; hsa-mir-3607-5p
Nearest miRNA
hsa-mir-1244-3/Upstream/6132060; hsa-let-7i/Downstream/406967;
Nearest TSS
ENST00000382841/Upstream/66948; ENST00000540733/Downstream/90572;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/1180175, chr12-CpG: 92/Downstream/756568
Upstream sequence
aggcatatattggtaaatagagtagttgcaaggattaaaagtgctaaaagagataaaacatgtaaagcgcaatgcctgaaaaaaaaacatatgctcaata
Downstream sequence
aatgttatctactgttATCAAAAAGTAGCATCACTAAGGTTAGTACAACCTTTCAAAGTAACCAAAATTATTTTGTTCTGCTTCTTTTATTCCTATTCCC
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate