Basic Information
VIS ID
TVIS44031619
Fusion event
HTLV-1-TTC23L integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr5
Cytoband
p13.2
Reference genome
NCBI36/hg18
Start
34887241/34851379 (Hg38)
End
34887241/34851379 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA5A
Target gene
TTC23L
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-10397/Upstream/2456904; hsa-mir-103a-1/Downstream/1296513;
Nearest TSS
ENST00000502646/Upstream/10707; ENST00000510834/Downstream/63422;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/11860, chr5-CpG: 83/Downstream/63809
Upstream sequence
AGGAAAAGGGAAGCAATATATTTGGGCCATAATGAGGCTGGATATCAGCAAAGCTTTTGAAAAAATTAAAATTGAGTTCACTTCTCAGTTATTGATCTCA
Downstream sequence
GAATATATTCTCCTTCTTAGGGCTCTATAGGCCCTTTTACACCCATTTATTTTTAATGCAACTTTAGATTCATTTATTGATGTGGCAAGATCACAGGTAG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
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