Basic Information
VIS ID
TVIS44031653
Fusion event
HTLV-1-ARHGAP21 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr10
Cytoband
p12.1
Reference genome
NCBI36/hg18
Start
25024241/24695306 (Hg38)
End
25024241/24695306 (Hg38)
Orient
-
Location type
Intronic
Target gene
ARHGAP21
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-21-5p ; hsa-mir-361-3p ; hsa-mir-183-5p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-4677-5p ; hsa-mir-190a-3p ; hsa-mir-22-5p ; hsa-mir-2116-5p ; hsa-mir-3182 ; hsa-mir-5011-5p ; hsa-mir-1277-5p
Nearest miRNA
hsa-mir-1265/Upstream/419525; hsa-mir-107/Downstream/3593952;
Nearest TSS
ENST00000439456/Upstream/72464; ENST00000610158/Downstream/11324;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/999257, chr10-CpG: 209/Downstream/27362
Upstream sequence
catgctatgtgtcatcccctacccttgagtgtgggctagacctagcgatttacttctaataaatagataaatagaatctagggtgggtgcagtggctcac
Downstream sequence
gcctataatcccagcattttcagaggccgaggcaggtggatcacttgaaatcatgagtttaagaccagcccggccaacgtggcaaaaccccgtctctact
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate