Basic Information
VIS ID
TVIS44031666
Fusion event
HTLV-1-SLC2A6 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr9
Cytoband
q34.2
Reference genome
NCBI36/hg18
Start
135332403/133477460 (Hg38)
End
135332403/133477460 (Hg38)
Orient
-
Location type
Intronic
Target gene
SLC2A6
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-92a-3p ; hsa-mir-4701-5p ; hsa-mir-129-5p ; hsa-mir-3149 ; hsa-mir-4715-3p ; hsa-mir-6867-5p ; hsa-mir-1227-3p ; hsa-mir-500b-3p ; hsa-mir-208b-5p ; hsa-mir-208a-5p ; hsa-mir-3665 ; hsa-mir-3674 ; hsa-mir-4464 ; hsa-mir-4662a-5p ; hsa-mir-4748 ; hsa-mir-5087 ; hsa-mir-657
Nearest miRNA
hsa-let-7a-1/Upstream/425401; hsa-mir-126/Downstream/901951;
Nearest TSS
ENST00000422679/Upstream/15289; ENST00000393060/Downstream/1615;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/2319, chr9-CpG: 83/Downstream/1398
Upstream sequence
AGTCAAGCACTTgaaacagggagcctcctgtcttcaaggaacagccatttgttagggatgcccaaacggggaattctgctctaaggaagaggtgctgcgc
Downstream sequence
cacatatccacagtggttctgtccagcctgatgttTAAATGTCTAATATTTTAATACAGGAGAATTCTGTGACTTGAAGGTACTGGGCTTTAAGATTTGG
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate