Basic Information
VIS ID
TVIS44031668
Fusion event
HTLV-1-PCM1 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr8
Cytoband
p22
Reference genome
NCBI36/hg18
Start
17851265/17949476 (Hg38)
End
17851265/17949476 (Hg38)
Orient
-
Location type
Intronic
Target gene
PCM1
miRNAs that regulate target gene
hsa-mir-33a-5p ; hsa-mir-129-5p ; hsa-mir-8055
Nearest miRNA
hsa-mir-124-1/Upstream/267819; hsa-mir-10400/Downstream/4295490;
Nearest TSS
ENST00000518652/Upstream/12300; ENST00000517836/Downstream/8182;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/25713, chr8-CpG: 103/Downstream/134314
Upstream sequence
TAGAGTTTTGACTAGACATATAGGATTCTATATAGCCTTGAAATTCTCAGTTCTCAGTGGAAAAAAGGTAGTGTTTTCCTTTAAAACAGAAGCAATTTAT
Downstream sequence
AACTAATTGTCttttttctttatcttttttttttttttgagacaggatcttgctctgtcacccaggctggaatacagtgggcgtgatcttggctcactgc
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate