Basic Information
VIS ID
TVIS44031671
Fusion event
HTLV-1-MYO1E integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr15
Cytoband
q22.2
Reference genome
NCBI36/hg18
Start
57397246/59317755 (Hg38)
End
57397246/59317755 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA15A
Target gene
MYO1E
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-30b-5p ; hsa-mir-93-5p ; hsa-let-7b-5p
Nearest miRNA
hsa-mir-10393/Upstream/146493; hsa-mir-11181/Downstream/2986903;
Nearest TSS
ENST00000557528/Upstream/52758; ENST00000558900/Downstream/54772;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/110616, chr15-CpG: 130/Downstream/53909
Upstream sequence
CTTCGGAACAGTAAACCCTGTGTAAGAAAGGGAGGCAGAACTGGGGGACAGATTTAGGAGAACAAATTTTCTGGCTTGTCAGGGCCTAGGGGTGCTAAAG
Downstream sequence
ATGAGCAATGGAAGAAGAGATGGAGAGAATGCTGGTGTGACAGAGCGAGGGCGTGAAACAgtcaggaacttttctaagtccttcatgtgggctaattcaa
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate