Basic Information
VIS ID
TVIS44031679
Fusion event
HTLV-1-DNAJC5 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr20
Cytoband
q13.33
Reference genome
NCBI36/hg18
Start
62014701/63912904 (Hg38)
End
62014701/63912904 (Hg38)
Orient
-
Location type
Intronic
Target gene
DNAJC5
miRNAs that regulate target gene
hsa-mir-7-5p ; hsa-mir-93-3p ; hsa-mir-23b-3p ; hsa-mir-15b-5p ; hsa-mir-34a-5p ; hsa-mir-31-5p
Nearest miRNA
hsa-mir-1-1/Upstream/626038; hsa-mir-1914/Downstream/6545;
Nearest TSS
ENST00000382410/Upstream/17722; ENST00000623569/Downstream/28705;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/17218, chr20-CpG: 72/Downstream/6456
Upstream sequence
caccatgttggccaggatggtcttgatctcctgacctcgtgatctggccaccttggcctcccaaagtgctgggatgacaggtttggccaccgtgcccggc
Downstream sequence
cGGCAGTCAGTTTTTACATGGTTCATCACAGATTTTAAATTAAGATTCCCCAGCAGGATAAAAGAAATGCCAGTTGTATTTTATTTTTCGTATTTGTATT
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate