Basic Information
VIS ID
TVIS44031694
Fusion event
HTLV-1-MSL2 integration
Validated
No
Detection method
HTS
Data source
Curated
Sample type
Nontumor
Disease
Not given
Quality evaluation
Normal
Reported year
2019
PubMed ID
30307560
Virus Sequence
Virus name
HTLV-1
Subtype
HTLV-1c
Reference genome
KF242506
Host Sequence
Chromosome
chr3
Cytoband
q22.3
Reference genome
NCBI36/hg18
Start
137392121/136190589 (Hg38)
End
137392121/136190589 (Hg38)
Orient
+
Location type
Intronic
Target gene
MSL2
miRNAs that regulate target gene
hsa-mir-30d-5p ; hsa-mir-30a-5p ; hsa-mir-578 ; hsa-mir-192-3p ; hsa-mir-664b-3p ; hsa-mir-5696 ; hsa-mir-579-3p ; hsa-mir-6853-3p ; hsa-mir-569 ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-655-5p ; hsa-mir-153-5p ; hsa-mir-1250-3p ; hsa-mir-33a-3p ; hsa-mir-409-3p ; hsa-mir-135b-3p ; hsa-mir-4691-5p ; hsa-mir-6792-3p ; hsa-mir-2276-3p ; hsa-mir-4772-3p ; hsa-mir-885-5p ; hsa-mir-4686 ; hsa-mir-296-3p ; hsa-mir-483-3p ; hsa-mir-136-5p ; hsa-mir-3943 ; hsa-mir-887-5p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-6807-5p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-7160-5p ; hsa-mir-4722-5p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-1827 ; hsa-mir-1233-3p ; hsa-mir-1225-3p ; hsa-mir-4649-3p ; hsa-mir-665 ; hsa-mir-4768-3p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-4323
Nearest miRNA
hsa-let-7g/Upstream/1752683; hsa-mir-1224/Downstream/15375287;
Nearest TSS
ENST00000440867/Upstream/88486; ENST00000465423/Downstream/3965;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/224064, chr3-CpG: 200/Downstream/4766
Upstream sequence
aactatgactgcaccactgcactccagcctgggtgacaaaacaagattgtctcaaaaaaaaaaaaaaaggaaaaTATTCATGTTCCCGAGTTTGACCATG
Downstream sequence
ATACTTTCCAAGTTATCTCCAAGAATAGTATTTTTCCATTTAACATGACCCTCCAATCCTAACAGGATTTTTGATTGTATACATCAGACTTGTTACATCA
Reference
Turpin, J., et al. Impact of Hepatitis B Virus Coinfection on Human T-Lymphotropic Virus Type 1 Clonality in an Indigenous Population of Central Australia. J Infect Dis ,2019,219(4): 562-567.
Curate